GLI3 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-91222-60uL | 60uL | £210.00 |
Quantity:
E-AB-91222-120uL | 120uL | £291.00 |
Quantity:
E-AB-91222-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Images
Further Information
Abbreviation:
GLI3
Background:
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
169kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
A synthetic peptide of human GLI3
ObservedMW:
250kDa
Purification method:
Affinity purification
Target Synonym:
GLI3;ACLS;GCPS;GLI3-190;GLI3FL;PAP-A;PAPA;PAPA1;PAPB;PHS;PPDIV
UNIProt ID:
P10071