ZNF384 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91377-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91377-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91377-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
ZNF384
Background:
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
50kDa/56kDa/63kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human ZNF384
ObservedMW:
70KDa
Purification method:
Affinity purification
Target Synonym:
ZNF384;CAGH1;CAGH1A;CIZ;ERDA2;NMP4;NP;TNRC1
UNIProt ID:
Q8TF68