PGAM5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91403-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91403-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91403-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
PGAM5
Background:
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
28kDa/32kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PGAM5
ObservedMW:
28KDa/30KDa
Purification method:
Affinity purification
Target Synonym:
PGAM5;BXLBV68
UNIProt ID:
Q96HS1