CCDC88A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91437-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91437-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91437-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
CCDC88A
Background:
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
207kDa/212kDa/215kDa/216kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CCDC88A
ObservedMW:
220kDa
Purification method:
Affinity purification
Target Synonym:
CCDC88A;APE;GIRDIN;GIV;GRDN;HkRP1;KIAA1212;PEHO;girdin
UNIProt ID:
Q3V6T2