NFATC2IP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91450-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91450-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91450-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
NFATC2IP
Background:
In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
13kDa/15kDa/45kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human NFATC2IP
ObservedMW:
45kDa
Purification method:
Affinity purification
Target Synonym:
NFATC2IP;ESC2;NIP45;RAD60
UNIProt ID:
Q8NCF5