SDHD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91480-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91480-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91480-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
SDHD
Background:
This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
9kDa/12kDa/15kDa/17kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human SDHD
ObservedMW:
17kDa
Purification method:
Affinity purification
Target Synonym:
SDHD;CBT1;CII-4;CWS3;PGL;PGL1;QPs3;SDH4;cybS
UNIProt ID:
O14521