NPRL2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91550-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91550-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91550-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
NPRL2
Background:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
23kDa/43kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human NPRL2
ObservedMW:
44kDa
Purification method:
Affinity purification
Target Synonym:
NPRL2;FFEVF2;NPR2;NPR2L;TUSC4;NPR2-like
UNIProt ID:
Q8WTW4