Insulin Receptor Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91652-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91652-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91652-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
Insulin Receptor
Background:
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
155kDa/156kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IP 1:50-1:200
Immunogen:
Recombinant fusion protein of human INSR
ObservedMW:
110kDa/220kDa
Purification method:
Affinity purification
Target Synonym:
CD220;HHF5;INSR
UNIProt ID:
P06213