RNF20 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91760-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91760-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91760-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
RNF20
Background:
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
113kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human RNF20
ObservedMW:
114kDa
Purification method:
Affinity purification
Target Synonym:
RNF20;BRE1;BRE1A;hBRE1
UNIProt ID:
Q5VTR2