PSMA/FOLH1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91793-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91793-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91793-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
PSMA/FOLH1
Background:
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
9kDa/12kDa/50kDa/78kDa/80kDa/82kDa/84kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human PSMA/FOLH1
ObservedMW:
105KDa
Purification method:
Affinity purification
Target Synonym:
FGCP;FOLH;GCP2;GCPII;NAALAD1;NAALAdase;PSM;PSMA;mGCP;FOLH1
UNIProt ID:
Q04609