B4GALT2 Polyclonal Antibody

Elabscience
Product Code: E-AB-91819
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-91819-60uL60uL£210.00
Quantity:
E-AB-91819-120uL120uL£291.00
Quantity:
E-AB-91819-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Western blot analysis of extracts of various cell lines using B4GALT2 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using B4GALT2 Polyclonal Antibody at 1:1000 dilution.

Documents

Further Information

Abbreviation:
B4GALT2
Background:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human B4GALT2
ObservedMW:
42kDa
Purification method:
Affinity purification
Target Synonym:
B4Gal-T2;B4Gal-T3;beta4Gal-T2;B4GALT2
UNIProt ID:
O60909