SPG20 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91853-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91853-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91853-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
SPG20
Background:
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
72kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human SPG20
ObservedMW:
73kDa
Purification method:
Affinity purification
Target Synonym:
SPARTIN;TAHCCP1;SPG20;spartin
UNIProt ID:
Q8N0X7