ERCC6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91996-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91996-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91996-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
ERCC6
Background:
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
168kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
A synthetic peptide of human ERCC6
ObservedMW:
168KDa
Purification method:
Affinity purification
Target Synonym:
CSB;CKN2;COFS;ARMD5;COFS1;POF11;RAD26;UVSS1;CSB-PGBD3;ERCC6
UNIProt ID:
Q03468