H2-Aa Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92020-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92020-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92020-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
H2-Aa
Background:
Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system; retina; and thymus primordium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); glomerulonephritis (multiple); hematologic cancer (multiple); and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
28kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of mouse H2-Aa
ObservedMW:
28KDa
Purification method:
Affinity purification
Target Synonym:
Ia1;H2Aa;Ia-1;H-2Aa;Aalpha;IAalpha;I-Aalpha;H2-Aa
UNIProt ID:
P14434