Topors Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92079-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92079-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92079-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
Topors
Background:
Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of mouse Topors
ObservedMW:
119kDa
Purification method:
Affinity purification
Target Synonym:
AW105885;LUN;TP53BPL;p53BP3/LUN;Topors
UNIProt ID:
Q80Z37