NTRK1/NTRK2/NTRK3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92128-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92128-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92128-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
NTRK1/NTRK2/NTRK3
Background:
Neurotrophic tyrosine kinase (NTRK) is a family of receptor tyrosine kinase.The NTRK gene family contains three members, NTRK1, NTRK2 and NTRK3, which produce TRKA, TRKB and TRKC proteins, respectively.TRK kinases leads to cell differentiation and may play important roles in normal neural functions.Rearrangements in the NTRK genes can result in two genes fusing together and producing altered TRK proteins, which can lead to uncontrolled growth of cancer cells. Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are an actionable biomarker for cancer therapy and can be found in over 25 different types of cancer.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
A synthetic peptide of human NTRK1/NTRK2/NTRK3
ObservedMW:
100KDa
Purification method:
Affinity purification
UNIProt ID:
P04629/Q16620/Q16288