KCNQ2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92142-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92142-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92142-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
KCNQ2
Background:
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
44kDa/92kDa/93kDa/94kDa/95kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human KCNQ2
ObservedMW:
95KDa
Purification method:
Affinity purification
Target Synonym:
KCNQ2;BFNC;EBN;EBN1;ENB1;HNSPC;KCNA11;KV7.2
UNIProt ID:
O43526