ITPR2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92150-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92150-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92150-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
ITPR2
Background:
The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human ITPR2
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
ANHD;CFAP48;INSP3R2;IP3R2;ITPR2
UNIProt ID:
Q14571