PHGDH Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92164-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92164-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92164-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
PHGDH
Background:
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
56kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PHGDH
ObservedMW:
57KDa
Purification method:
Affinity purification
Target Synonym:
PHGDH;3-PGDH;3PGDH;HEL-S-113;NLS;NLS1;PDG;PGAD;PGD;PGDH;PHGDHD;SERA
UNIProt ID:
O43175