PCNT Polyclonal Antibody
Code | Size | Price |
---|
E-AB-92179-60uL | 60uL | £210.00 |
Quantity:
E-AB-92179-120uL | 120uL | £291.00 |
Quantity:
E-AB-92179-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Images
Further Information
Abbreviation:
PCNT
Background:
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
378kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PCNT
ObservedMW:
251KDa/378KDa
Purification method:
Affinity purification
Target Synonym:
KEN; PCN; MOPD2; PCNT2; PCNTB; PCTN2; SCKL4
UNIProt ID:
O95613