4-1BB/CD137 Polyclonal Antibody

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Elabscience
Product Code: E-AB-92202
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-92202-60uL60uL£210.00
Quantity:
E-AB-92202-120uL120uL£291.00
Quantity:
E-AB-92202-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Mouse spleen using 4-1BB/CD137 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
2 / 2
Immunohistochemistry of paraffin-embedded Human spleen using 4-1BB/CD137 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
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Immunohistochemistry of paraffin-embedded Mouse spleen using 4-1BB/CD137 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded Human spleen using 4-1BB/CD137 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Documents

Further Information

Abbreviation:
4-1BB/CD137
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
27kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human 4-1BB/CD137
ObservedMW:
27kDa
Purification method:
Affinity purification
Target Synonym:
TNFRSF9;4-1BB;CD137;CDw137;ILA
UNIProt ID:
Q07011