TIGAR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92238-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92238-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92238-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
TIGAR
Background:
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
30kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
A synthetic peptide of human TIGAR
ObservedMW:
30kDa
Purification method:
Affinity purification
Target Synonym:
FR2BP; C12orf5
UNIProt ID:
Q9NQ88