Lrwd1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-92356-60uL | 60uL | £210.00 |
Quantity:
E-AB-92356-120uL | 120uL | £291.00 |
Quantity:
E-AB-92356-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Images
Further Information
Abbreviation:
Lrwd1
Background:
The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
70kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human Lrwd1
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
LRWD1; CENP-33; ORCA; leucine-rich repeat and WD repeat-containing protein 1
UNIProt ID:
Q9UFC0