(KO Validated) FH Polyclonal Antibody

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Elabscience
Product Code: E-AB-92357
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-92357-60uL60uL£224.00
Quantity:
E-AB-92357-120uL120uL£317.00
Quantity:
E-AB-92357-200uL200uL£465.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Western blot analysis of extracts from wild type(WT) and FH knockout (KO) 293T(KO) cells, using FH Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts from wild type(WT) and FH knockout (KO) 293T(KO) cells, using FH Polyclonal Antibody at 1:1000 dilution.

Documents

Further Information

Abbreviation:
FH
Background:
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
50kDa/54kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human FH
ObservedMW:
49KDa
Purification method:
Affinity purification
Target Synonym:
FH; FMRD; HLRCC; LRCC; MCL; MCUL1; fumarate hydratase
UNIProt ID:
P07954