MLH1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92376-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92376-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92376-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
MLH1
Background:
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
58kDa/73kDa/84kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human MLH1
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
MLH1; COCA2; FCC2; HNPCC; HNPCC2; hMLH1; mutL homolog 1
UNIProt ID:
P40692