B-Raf Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92401-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92401-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92401-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
B-Raf
Background:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
84kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human B-Raf
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
BRAF; B-RAF1; B-raf; BRAF1; NS7; RAFB1; serine/threonine-protein kinase B-raf
UNIProt ID:
P15056