Cullin 1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92419-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92419-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92419-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
Cullin 1
Background:
The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1?3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
89kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human Cullin 1
ObservedMW:
90KDa
Purification method:
Affinity purification
Target Synonym:
CUL1; MGC149834; MGC149835; cullin-1
UNIProt ID:
Q13616