SEC61B Polyclonal Antibody

Elabscience
Product Code: E-AB-92431
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-92431-60uL60uL£210.00
Quantity:
E-AB-92431-120uL120uL£291.00
Quantity:
E-AB-92431-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

1 / 2
Immunofluorescence analysis of NIH/3T3 cells using SEC61B Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
2 / 2
Immunofluorescence analysis of U2OS cells using SEC61B Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Immunofluorescence analysis of NIH/3T3 cells using SEC61B Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using SEC61B Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
SEC61B
Background:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
9kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
A synthetic peptide of human SEC61B
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
SEC61B; Sec61 translocon beta subunit
UNIProt ID:
P60468