OGG1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92460-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92460-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92460-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
OGG1
Background:
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
22kDa/36kDa/38kDa/39kDa/40kDa/45kDa/47kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human OGG1
ObservedMW:
36kDa
Purification method:
Affinity purification
Target Synonym:
OGG1;HMMH;HOGG1;MUTM;OGH1
UNIProt ID:
O15527