COL4A4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92462-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92462-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92462-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
COL4A4
Background:
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
164kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human COL4A4
ObservedMW:
160KDa
Purification method:
Affinity purification
Target Synonym:
BFH; ATS2; CA44
UNIProt ID:
P53420