MRE11 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92474-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92474-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92474-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
MRE11
Background:
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
77kDa/80kDa/81kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human MRE11
ObservedMW:
81KDa
Purification method:
Affinity purification
Target Synonym:
MRE11;ATLD;HNGS1;MRE11A;MRE11B
UNIProt ID:
P49959