CD215/IL-15R alpha Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92503-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92503-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92503-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
CD215/IL-15R alpha
Background:
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
15-28kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human CD215/IL-15R alpha
ObservedMW:
60KDa
Purification method:
Affinity purification
Target Synonym:
IL15RA;CD215
UNIProt ID:
Q13261