Elabscience

PMEL Polyclonal Antibody

Product Code:
 
E-AB-92644
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of A375 cells using PMEL Polyclonal Antibody at 1:1000 dilution.
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Immunofluorescence analysis of A375 cells using PMEL Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of A375 cells using PMEL Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of A375 cells using PMEL Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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E-AB-92644-60uL60uL£210.00
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E-AB-92644-120uL120uL£291.00
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E-AB-92644-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PMEL
Background:
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
60kDa/66kDa/70kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PMEL
ObservedMW:
80KDa/105KDa
Purification method:
Affinity purification
Target Synonym:
PMEL;D12S53E;ME20;ME20-M;ME20M;P1;P100;PMEL17;SI;SIL;SILV;gp100
UNIProt ID:
P40967

Documents