RBFOX1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92804-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92804-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92804-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
RBFOX1
Background:
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
40kDa/42kDa/44kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:100-1:200
Immunogen:
Recombinant fusion protein of human RBFOX1
ObservedMW:
45-50KDa
Purification method:
Affinity purification
Target Synonym:
RBFOX1;2BP1;A2BP1;FOX-1;FOX1;HRNBP1
UNIProt ID:
Q9NWB1