Lipin 1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-92878-60uL | 60uL | £210.00 |
Quantity:
| E-AB-92878-120uL | 120uL | £291.00 |
Quantity:
| E-AB-92878-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
Lipin 1
Background:
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
50kDa/98kDa/99-107kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human Lipin 1
ObservedMW:
113kDa
Purification method:
Affinity purification
Target Synonym:
LPIN1;PAP1;lipin 1
UNIProt ID:
Q14693