CNOT7 Polyclonal Antibody

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Elabscience
Product Code: E-AB-92923
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-92923-60uL60uL£210.00
Quantity:
E-AB-92923-120uL120uL£291.00
Quantity:
E-AB-92923-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Mouse brain using CNOT7 Polyclonal Antibody at dilution of 1:50 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
2 / 2
Immunohistochemistry of paraffin-embedded Human colon using CNOT7 Polyclonal Antibody at dilution of 1:50 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
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Immunohistochemistry of paraffin-embedded Mouse brain using CNOT7 Polyclonal Antibody at dilution of 1:50 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded Human colon using CNOT7 Polyclonal Antibody at dilution of 1:50 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Documents

Further Information

Abbreviation:
CNOT7
Background:
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
28kDa/32kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human CNOT7
ObservedMW:
33kDa
Purification method:
Affinity purification
Target Synonym:
CNOT7;CAF-1;CAF1;Caf1a;hCAF-1
UNIProt ID:
Q9UIV1