SH3PXD2A Polyclonal Antibody

Elabscience
Product Code: E-AB-92960
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-92960-60uL60uL£210.00
Quantity:
E-AB-92960-120uL120uL£291.00
Quantity:
E-AB-92960-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

1 / 2
Western blot analysis of extracts of HeLa cells using SH3PXD2A Polyclonal Antibody
2 / 2
Immunofluorescence analysis of L929 cells using SH3PXD2A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Western blot analysis of extracts of HeLa cells using SH3PXD2A Polyclonal Antibody
Immunofluorescence analysis of L929 cells using SH3PXD2A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
SH3PXD2A
Background:
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs, NADPH oxidases (NOXs and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
102kDa/121kDa/125kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human SH3PXD2A
ObservedMW:
100kDa
Purification method:
Affinity purification
Target Synonym:
SH3PXD2A;FISH;SH3MD1;TKS5
UNIProt ID:
Q5TCZ1