MRP1/ABCC1 Polyclonal Antibody

Elabscience
Product Code: E-AB-93049
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-93049-60uL60uL£210.00
Quantity:
E-AB-93049-120uL120uL£291.00
Quantity:
E-AB-93049-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Western blot analysis of extracts of HepG2 cells using MRP1/ABCC1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of HeLa cells using MRP1/ABCC1 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of HepG2 cells using MRP1/ABCC1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of HeLa cells using MRP1/ABCC1 Polyclonal Antibody at 1:1000 dilution.

Documents

Further Information

Abbreviation:
MRP1/ABCC1
Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
151-172kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MRP1/ABCC1
ObservedMW:
210kDa
Purification method:
Affinity purification
Target Synonym:
ABCC1;ABC29;ABCC;GS-X;MRP;MRP1
UNIProt ID:
P33527