ALKBH5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93063-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93063-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93063-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
ALKBH5
Background:
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
43kDa/44kDa/52kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human ALKBH5
ObservedMW:
40-50KDa
Purification method:
Affinity purification
Target Synonym:
ALKBH5;ABH5;OFOXD;OFOXD1
UNIProt ID:
Q6P6C2