SETD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93066-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93066-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93066-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
SETD2
Background:
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
175kDa/192kDa/287kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human SETD2
ObservedMW:
288kDa
Purification method:
Affinity purification
Target Synonym:
SETD2;HBP231;HIF-1;HIP-1;HSPC069;HYPB;KMT3A;LLS;SET2;p231HBP
UNIProt ID:
Q9BYW2