TAK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93071-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93071-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93071-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
TAK1
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
53kDa/56kDa/64kDa/67kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human TAK1
ObservedMW:
67KDa
Purification method:
Affinity purification
Target Synonym:
CSCF;FMD2;MEKK7;TAK1;TGF1a;MAP3K7
UNIProt ID:
O43318