SLC7A11/xCT Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93104-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93104-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93104-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
SLC7A11/xCT
Background:
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
55kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human SLC7A11/xCT
ObservedMW:
55KDa
Purification method:
Affinity purification
Target Synonym:
SLC7A11;CCBR1;xCT
UNIProt ID:
Q9UPY5