IDO1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93146-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93146-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93146-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
IDO1
Background:
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
45kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human IDO1
ObservedMW:
40KDa
Purification method:
Affinity purification
Target Synonym:
IDO1;IDO;IDO-1;INDO;indoleamine 2
UNIProt ID:
P14902