GPBAR1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93270-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93270-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93270-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
GPBAR1
Background:
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
35kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
A synthetic peptide of human GPBAR1
ObservedMW:
35KDa
Purification method:
Affinity purification
Target Synonym:
BG37; TGR5; M-BAR; GPCR19; GPR131
UNIProt ID:
Q8TDU6