TYK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-93276-60uL | 60uL | £210.00 |
Quantity:
| E-AB-93276-120uL | 120uL | £291.00 |
Quantity:
| E-AB-93276-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
TYK2
Background:
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
133kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human TYK2
ObservedMW:
134KDa
Purification method:
Affinity purification
Target Synonym:
TYK2;IMD35;JTK1
UNIProt ID:
P29597