DNM1L Polyclonal Antibody

Elabscience
Product Code: E-AB-93281
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-93281-60uL60uL£210.00
Quantity:
E-AB-93281-120uL120uL£291.00
Quantity:
E-AB-93281-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

1 / 3
Immunofluorescence analysis of NIH/3T3 cells using DRP1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
2 / 3
Immunofluorescence analysis of PC-12 cells using DRP1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
3 / 3
Immunofluorescence analysis of U2OS cells using DRP1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Immunofluorescence analysis of NIH/3T3 cells using DRP1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of PC-12 cells using DRP1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using DRP1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
DNM1L
Background:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human DNM1L
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
DNM1L; DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; dynamin 1 like
UNIProt ID:
O00429