FXN/Frataxin Polyclonal Antibody

Elabscience
Product Code: E-AB-93295
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-93295-60uL60uL£210.00
Quantity:
E-AB-93295-120uL120uL£291.00
Quantity:
E-AB-93295-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

1 / 8
Immunohistochemistry of paraffin-embedded human liver using FXN / Frataxin Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
2 / 8
Immunohistochemistry of paraffin-embedded mouse heart using FXN / Frataxin Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
3 / 8
Immunohistochemistry of paraffin-embedded rat kidney using FXN / Frataxin Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
4 / 8
Immunofluorescence analysis of L929 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
5 / 8
Immunofluorescence analysis of C6 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
6 / 8
Immunofluorescence analysis of L929 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
7 / 8
8 / 8
Immunofluorescence analysis of L929 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Immunohistochemistry of paraffin-embedded human liver using FXN / Frataxin Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded mouse heart using FXN / Frataxin Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded rat kidney using FXN / Frataxin Polyclonal Antibody at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunofluorescence analysis of L929 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using FXN / Frataxin Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
FXN/Frataxin
Background:
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
19kDa/21kDa/23kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human FXN / Frataxin
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
FXN; CyaY; FA; FARR; FRDA; X25; frataxin
UNIProt ID:
Q16595