MyD88 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-93306-60uL | 60uL | £210.00 |
Quantity:
E-AB-93306-120uL | 120uL | £291.00 |
Quantity:
E-AB-93306-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Images
Further Information
Abbreviation:
MyD88
Background:
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
15kDa/20kDa/28kDa/31kDa/33kDa/34kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human MyD88
ObservedMW:
33KDa
Purification method:
Affinity purification
Target Synonym:
MYD88; MYD88D; myeloid differentiation primary response 88
UNIProt ID:
Q99836