FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]

Elabscience
Product Code: E-AB-F1192C
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-F1192C-50Tests50Tests£145.00
Quantity:
E-AB-F1192C-100Tests100Tests£184.00
Quantity:
E-AB-F1192C-100Testsx2100Testsx2£267.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: Rat IgG2a, κ
Antibody Clone: RMT3-23
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Images

1 / 1
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD366/Tim-3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).

C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD366/Tim-3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).

Documents

Further Information

Abbreviation:
CD366/Tim-3
Background:
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
FITC
GeneID:
84868
Target Synonym:
TIM3; TIMD3;HAVcr-2;TIMD-3;
UNIProt ID:
Q8VIM0
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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