Elab Fluor® 647 Anti-Mouse CD163 Antibody[S15049F]

Elabscience
Product Code: E-AB-F1295UM
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-F1295UM-25ug25ug£164.00
Quantity:
E-AB-F1295UM-100ug100ug£297.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: Rat IgG2a, κ
Antibody Clone: S15049F
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Images

1 / 1
C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® 647 Anti-Mouse CD163 Antibody (Left). Bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® 647 Rat IgG2a,κ Isotype Control (Right).

C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® 647 Anti-Mouse CD163 Antibody (Left). Bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® 647 Rat IgG2a,κ Isotype Control (Right).

Documents

Further Information

Abbreviation:
CD163
Background:
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
0.5 mg/mL
Conjugation:
Elab Fluor® 647
GeneID:
93671
Target Synonym:
M130; MM130; SCARI1;
UNIProt ID:
Q2VLH6
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 ug/10^6 cells in 100 uL volume].

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